At least 74 children have been killed and more than 100,000 people displaced in Yemen since fighting there intensified two weeks ago, according to the UN's children's agency.
UNICEF said hospitals are struggling to treat the large numbers of wounded with inefficient supplies and some medical facilities have come under attack.
Saudi Arabia has in recent weeks led an air campaign against Yemen's Shi'ite rebels and their allies.
At least three health workers, including an ambulance driver, have been killed in attacks, the agency said.
UNICEF also said the violence has disrupted water supplies in parts of southern Yemen and sewage is overflowing in some locations, raising the risk of an outbreak of disease.
Children are especially vulnerable as the fighting continues, said UNICEF's Yemen representative Julien Harneis.
He said: "They are being killed, maimed and forced to flee their homes, their health threatened and their education interrupted."
As well as the dozens who have been killed, 44 have also been wounded, according to UNICEF.
The fighting pits allies of Yemen's embattled president, Abed Rabbo Mansour Hadi, against rebels known as Houthis and their allies, soldiers loyal to Hadi's predecessor, the ousted autocrat Ali Abdullah Saleh.
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Gallery: Aftermath Of Airstrikes By Saudi Arabia And Gulf Allies - 26 March
People search for survivors under the rubble of houses destroyed by an air strike near Sana'a Airport in Yemen. Continue through for more images
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